ipsae

The `protein-qc` skill provides research-backed quality control metrics and filtering thresholds for evaluating protein designs. It helps developers check sequence liabilities, compute biophysical and interface properties, and create multi-stage filtering pipelines. Use it for pre-screening designs based on pLDDT, ipTM, PAE, and other benchmarks before experimental testing.

This skill provides expert guidance for planning, troubleshooting, and interpreting Surface Plasmon Resonance (SPR) and Bio-Layer Interferometry (BLI) binding experiments. It helps developers choose between SPR and BLI platforms using a detailed decision matrix based on factors like sensitivity, throughput, and sample requirements. Use it when designing kinetics studies or analyzing binding data artifacts.

This skill provides guidance for planning and troubleshooting SPR and BLI binding kinetics experiments. It helps developers choose between platforms, interpret data artifacts, and resolve poor binding signals. Key features include a decision matrix comparing SPR/BLI and troubleshooting for common experimental issues.

This skill provides expert guidance for planning, troubleshooting, and interpreting Surface Plasmon Resonance (SPR) and Bio-Layer Interferometry (BLI) binding kinetics experiments. It helps developers choose between SPR and BLI platforms using a detailed decision matrix and offers solutions for common issues like poor signal or data artifacts. Use it when designing or validating binding assays to ensure robust experimental results.