cdr3clustering
About
This skill clusters TCR/BCR clones by their CDR3 sequences using either GIANA or ClusTCR (both Faiss-based methods). It adds a `CDR3_Cluster` column to metadata for clonotype analysis, enabling identification of similar sequences and public clonotypes. Use it after ScRepCombiningExpression when VDJ data is present to analyze TCR convergence or prepare for epitope specificity analysis.
Quick Install
Claude Code
Recommendednpx skills add majiayu000/claude-skill-registry -a claude-code/plugin add https://github.com/majiayu000/claude-skill-registrygit clone https://github.com/majiayu000/claude-skill-registry.git ~/.claude/skills/cdr3clusteringCopy and paste this command in Claude Code to install this skill
GitHub Repository
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