polars-bio
About
polars-bio is a high-performance Python library for genomic interval operations and bioinformatics file I/O, built on Polars DataFrames. It provides fast, familiar DataFrame methods for tasks like finding overlaps, merging intervals, and calculating coverage, while supporting streaming and cloud-native file access. Use it when you need a faster, scalable alternative to bioframe for processing BED, VCF, BAM, or GFF files.
Quick Install
Claude Code
Recommendednpx skills add K-Dense-AI/claude-scientific-skills -a claude-code/plugin add https://github.com/K-Dense-AI/claude-scientific-skillsgit clone https://github.com/K-Dense-AI/claude-scientific-skills.git ~/.claude/skills/polars-bioCopy and paste this command in Claude Code to install this skill
GitHub Repository
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